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fludrocortisone will reduce the extent or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.fedratinib will improve the amount or outcome of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Check. Change dose of drugs which are CYP2C19 substrates as required.Steer clear of coad